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Indian Institute of Science Education and Research Bhopal
Chemistry
CHM 612: Advanced Organic Chemistry II (4)
Prerequisites: CHM 311, CHM 312
Reactions related to synthesis of 3 to 6 membered and higher carbocycles.
Miscellaneous reactions: (a) tandem/domino reaction, (b) multicomponent reaction (MCR), (c) remote functionalization.
Philosophy of synthetic design: Retrosynthesis, importance of reactivity, relation between functional groups, regio and stereocontrol, use of functional groups as a guide for retrosynthesis.
Concepts of atom, step and redox economy.
Total synthesis of natural products.
Suggested Readings :
- Clayden, J., Greeves, N., Warren, S., Wothers, S. Organic Chemistry, Oxford University Press, 2001.
- Wyatt, P., Warren, S. Organic Synthesis: Strategy and Control, Wiley, 2007.
- Warren, S. Organic Synthesis: The Disconnection Approach, Wiley, 1983.
- Nicolaou, K. C., Sorensen, E. Classics in Total Synthesis, Wiley-VCH, 2008.
- Nicolaou, K. C., Snyder, S. A. Classics in Total Synthesis-II, Wiley-VCH, 2003.
- Corey, E. J., Cheng, X-M. The Logic of Chemical Synthesis, Wiley, 1995.
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