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Indian Institute of Science Education and Research Bhopal

BIO 615: Epigenetics and Gene Regulation (4)

Introduction to theme; Chromatin, Epigenetics and Transcription, DNA methylation and demethylation, Histone modifications; Acetylation, Methylation, Phosphorylation, Ubiquitinylation, Sumoylation, Poly-ADP Ribosylation:, Heterochromatin; Histone variants; Nucleosome; Long non-coding RNA and chromatin; Epigenetics and alternative splicing; Epigenetics and mammalian development; Polycomb and Trithorax group proteins; Dosage compensation and Genomic imprinting; Epigenetics and Human Diseases, Cancer

Suggested Books:

• Thomas Jenuwein, Danny Reinberg, Marie-laure Caparros, C. David Allis, Epigenetics  1st Edition Cold Spring Harbor Laboratory Press, Usa 2008, ISBN-13 9780879698751
• Bryan M Turner, Chromatin and gene regulation, Jhon Wiley & Sons (asia) Pte Ltd 2001, ISBN-13 9780865427433
• Krishnarao Appasani, Epigenomics From Chromatin Biology to Therapeutics, Cambridge University Press 2012, ISBN-13: 978-1107003828
• Robert A. Meyers, Epigenetic Regulation and Epigenomics, John Wiley & Sons 2012, ISBN-13:978-3527326822

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