Office of Academic Affairs
Indian Institute of Science Education and Research Bhopal
CHM 416: Spectroscopy and its Application to Organic Molecules (4)
Prerequisites: CHM 311, CHM 312
Infrared spectroscopy: Theory of IR spectroscopy, Modes of stretching and bending, Fourier Transform Spectrometers, Background spectrum, Survey of important functional groups with examples, Chemical environment and chemical shift.
Nuclear Magnetic Resonance: Physical basis of Nuclear Magnetic Resonance spectroscopy, Chemical shift and Spin-spin coupling as functions of structure, Analysis of high-resolution NMR spectra, FT and pulse-NMR, NOE, 2D NMR (COSY, INADEQUATE, HMQC, HSQC, HMBC, NOESY, HETCOR, ROESY, TOCSY).
Mass spectroscopy: Principles of Mass Spectrometry, Ion sources (EI, CI, Field Ionization, FAB, Plasma desorption, Field desorption, Laser desorption, MALDI, Thermospray, API, ESI, APCI, APPI, Atmospheric pressure secondary ion mass spectrometry, inorganic ionization techniques, formation and fragmentation of ions, fragmentation reactions, Mass analyzers (Quadrople, Ion trap, ToF, Orbitrap, magnetic and electromagnetic analyzers), Ion cyclotron resonance and FT-MS.
Application of above techniques to organic chemistry and structural elucidation with exhaustive examples from latest publications.
Suggested Readings :
- Donald L. Pavia, Gary M. Lampman, George S. Kriz, James A. Vyvyan: Introduction to Spectroscopy, 4th Edition, Brookes Cole, 2008.
- Harald Gunther: NMR spectroscopy, Basic principles, concepts, and applications in chemistry, 2nd Ed., Wiley, 2001 (reprint)
- Timothy Claridge: High Resolution NMR Techniques in Organic Chemistry, 2nd Ed. Elsevier, 2009
- Edmond de Hoffmann, Vincent Stroobant: Mass Spectrometry, Principles and applications, 3rd Edition, Wiley, 2007
- Robert M. Silverstein, Francis X. Webster, David Kiemle: Spectrometric identification of organic compounds, 7th Edition, Wiley, 2005.
 Previous |
Back to Course List | Next  |