Office of Academic Affairs
Indian Institute of Science Education and Research Bhopal

CHM 343: Chemistry of Biological Systems (4)

Learning Objectives:

This course focuses on the Chemical aspects of Biological transformations. This course aims to introduce the chemical functionalities present in various classes of biological molecules, and discuss how transformation of these functionalities in Nature utilize the principles of Chemistry.

Course Contents:

Part A:

• Carbohydrates: Monosaccharide, polysaccharides, Mutarotation, Anomeric effects.
• Amino acids and Protein structure
• Fatty acid biosynthesis and degradation pathways
• Introduction to metabolism and bioenergetics.
• Oxidation and Reduction pathways in biological system.
• Chemistry of Garlic and Onion

Part B:

• Elements of life, Role of metal ion in biological functions,
• Metal nucleic acid interactions, Metalloproteins and metalloenzymes,
• Oxygen carrier proteins- Structure and role of haemoglobin, myoglobin, hemerythrin, hemocyanin.
• Electron transport proteins: Iron-Sulfur proteins, cytochromes.
• Redox enzyme: Mo, Fe, Cu, Zn-containing redox enzyme.
• Metal induced toxicity and chelation therapy: Platinum complexes and related anticancer drugs.

Suggested Books:

• Jeremy Berg, John Tymoczko, and Lubert Stryer Biochemistry (5th Edition)
• S. J. Lippard, J. M. Berg Principles of Bioinorganic Chemistry University Science Books
• Clayden, J., Greeves, N., Warren, S., Wothers, S. Organic Chemistry, Oxford University Press, 2001.

Previous

Back to Course List

Next